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Blueprint MedTech Cycle 3 – 5 Optimizer Awardees

Blueprint MedTech 3 – 5 Awardees

NIH’s Blueprint MedTech program has issued 26 Optimizer project awards over five competition cycles. These awards total over $68M. These projects will be administered by the two Blueprint MedTech Incubator Hubs—Cimit’s Center for Innovative NeuroTech Advancement (CINTA) and NeuroTech Harbor (NTH).

Blueprint MedTech Cycle 3 – 5 Optimizer awardees:

For additional details on the Optimizer awards, please see this NIBIB Science Highlight.

Awardee Institution Optimizer Project Title Funding NIH Institute(s)
Neurava A ML-based SUDEP risk stratification algorithm based on seizure and cardiorespiratory activity recorded from a novel wearable system NINDS
Arizona State University* Wireless, injectable neurostimulators (WINS) for treating chronic migraine (CM) HEAL Initiative
Motif Neurotech* Minimally invasive implants for treatment-resistant depression BRAIN Initiative
MicroLeads BRELLA: A Self-Expandable, Injectable Bioelectronic for Chronic Knee Pain HEAL Initiative
CraniUS CraniUS NeuroPASS NINDS
MuscleMetrix* Magnetomicrometry NIHCD/NCMRR, NINDS
Neurologic Solutions EpiScalp – Software application to assist neurologists in diagnosing epilepsy NINDS
AutonomUS* Reducing Opioid Use after Total Knee Replacement through Semi-automated AI-Enabled Ultrasound-Guided Robotic Adductor Canal Nerve Block HEAL Initiative
Craniosense* Development and clinical evaluation of a novel non-invasive intracranial pressure assessment and monitoring device NINDS
HEPIUS Lab* Implantable Ultrasound Transducer for Remote Spinal Cord Injury Monitoring NINDS
CoolSpine* Intrathecal Cooling Catheter to Provide Neuroprotection to Avoid Paraplegia resulting from Open and Endovascular Thoracic Aneurysm Repair NINDS

* is a graduate of the BPMT Seedlings Program (see descriptions from the Neurotech Harbor web page)

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NeuroTech Roadshow Podcast #1 in November 2025

The NTH Outreach Team is excited to announce the upcoming launch of our podcast, NeuroTech Roadshow. Beginning in November 2025, we will be publishing one podcast episode a month featuring industry experts, thought leaders, patients/patient advocates, and more to raise awareness of neurological disorders and facilitate the sharing of knowledge to accelerate neurotechnology advancement. The podcast will dive into topics including the neurological disorders that affect 1-in-3 people worldwide, cutting edge neuromedical interventions (both invasive and non-invasive), lived patient experience with neurological disorders, the ethics of neurotechnology, and more.

The Outreach Team is currently planning the first six episodes of the podcast, to be published from November 2025 through April 2026.

Episode one will feature Dr. Prasad Shivalkar, UCSF, and one of his patients from a clinical trial that was featured in the NYT. Episode two will feature Dr. Sri Sarma and her research into misdiagnosed non-epileptic seizures.

NeuroTech Roadshow Logo

NeuroTech Roadshow Podcast #2 in December 2025

The NTH Outreach Team is excited to announce the upcoming launch of our podcast, NeuroTech Roadshow. Beginning in November 2025, we will be publishing one podcast episode a month featuring industry experts, thought leaders, patients/patient advocates, and more to raise awareness of neurological disorders and facilitate the sharing of knowledge to accelerate neurotechnology advancement. The podcast will dive into topics including the neurological disorders that affect 1-in-3 people worldwide, cutting edge neuromedical interventions (both invasive and non-invasive), lived patient experience with neurological disorders, the ethics of neurotechnology, and more.

The Outreach Team is currently planning the first six episodes of the podcast, to be published from November 2025 through April 2026. Episode 2 will feature Dr. Sri Sarma and her research into misdiagnosed non-epileptic seizures.